Endocrine Abstracts

Background: Pregnancy is a state where changes in maternal physiology influence thyroid status. In addition, thyroid disease in mother can have substantial adverse outcome on the pregnancy and fetus. The objective of this study was to establish correlation of maternal TSH with PAPP-A, Beta HCG, Inhibin, uE3, AFP and HCG and compare pregnancy outcomes in subclinical hypothyroid pregnant women with euthyroid women.Methodology: 110 out of 150 singleton preg...

The intrauterine foetal environment is crucial for foetal survival and long term health. The insulin-like growth factors (IGF)-I and -II have a predominant role in fetal growth and development. Insulin-like growth factor 1 (IGF-1) is an anabolic hormone with several biological activities, such as proliferation, mitochondrial protection, cell survival, tissue growth and development.Aims & Objectives: To find the association of Maternal insulin Growth ...

Background: The intrauterine foetal environment is crucial for its survival and long term health. Intrauterine growth retardation of the foetus is a pregnancy specific disorder which involves the restriction in the physical and or mental growth of the foetus during the course of the pregnancy. Lactate dehydrogenase is an intracellular enzyme that converts lactic acid to pyruvic acid. It has been proposed as an important marker for liver diseases, myocardial, renal, and pulmona...

This study was planned to investigate the relationship between birth weight and IGF1, IGF binding protein-3 (IGFBP3), in neonates with normal growth (appropriate for gestational age: AGA) and retarded growth (small for gestational age: SGA). A total of 200 mothers were recruited, 120 serum samples were maternal and collected between gestational age of 32-38 weeks, 80 were cord blood from SGA and AGA fetus collected soon after delivery. 98 maternal samples and 48 cord blood sam...

Human papillomavirus (HPV) is one of the most common sexually transmitted viruses in reproductive age. About 80% of women will get at least one type of HPV at some point in their lifetime. Pregnancy is highly susceptible because decreased immunity during this period. There are few studies available from Indian sub-continent indicating a link between HPV infection and pregnancy. Association with various demographic factors in women would help in categorising those women who are...